Recombinant Mouse Serpin F2/Alpha-2-Antiplasmin Protein(C-6His)

Recombinant Mouse Serpin F2/Alpha-2-Antiplasmin Protein(C-6His)

Size

10µg

Catalog no.

PKSM041141-10µg

Price

267 EUR

Buy

Activity

NA

Fusion tag

C-6His

Accession

Q61247

Mol Mass

53.2 kDa

AP Mol Mass

70-85 kDa

Expressed Host

Human Cells

Sequence

Val28-Lys491

Group

recombinants

Latin name

Mus musculus

Source

Recombinants or rec. proteins

Purity

>95% as determined by reducing SDS-PAGE.

Stability and Storage

Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles

Synonym

Alpha-2-antiplasmin; Alpha-2-AP; Alpha-2-plasmin inhibitor; Alpha-2-PI; Serpin F2; Serpinf2

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,20% glycerol,1mM DTT,pH 8.0.

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Description

The Recombinant Mouse Serpin F2/Alpha-2-Antiplasmin Protein(C-6His) is a α- or alpha protein sometimes glycoprotein present in blood.

Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Background

Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver cirrhosis, there is decreased production of alpha 2-antiplasmin, leading to decreased inactivation of plasmin and an increase in fibrinolysis. Serpin F2 is major expressed on liver and kidney. Some other tissues such as muscle, intestine, central nervous system, and placenta also express Serpin F2 mRNA at a moderate level indicated that it is a key regulator of plasmin-mediated proteolysis in these tissues.