F7, Coagulation factor VII
Raised in
Hen
Verified reactivity
human
Molecular weight (expected | аpparent)
52 kDa
Protein number
P08709
Possible reactivity
primates
Purification
Total IgY
Clonality
Polyclonal
Clone
Polyclonal
TAIR number
Refer to NCBI
Verified applications
Western blot (WB)
References
to be added when available
Available ordering format
Liquid in 0.9% NaCl, 0.1% sodium azide
Immunogen
Purified full length recombinant protein P08709
How to reconstitute
See included datasheet or contact our support service
No reactivity
no confirmed exceptions from predicted reactivity known in the moment
Recommended dilutions for use
1: 5 000 - 1: 10 000 with standard ECL (WB), 1: 1000 - 1: 5 000 (ELISA)
Supplementary information
the antibody, in dilution 1: 10 000, will detect 1 ng of factor VII in immunoblotting
Notes
he IgY fraction is isolated by a two-step PEG precipitation procedure followed by ammonium sulphate precipitation
Connected products
AS00 001 | anti-Coagulation factor VIIa IMS01-015-308 | anti-Coagulation factor VIII AS05 058 | anti-Coagulation factor IXIMS01-137-306 | anti-Coagulation factor XIISecondary antibodies
Storage condition
store at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
Scientific context
Factor VII is a 52 kDa multi-domain, single chain plasma glycoprotein synthesised in the liver and having abnormal circulating concentration of between 400 and 600 g/L. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa through cleavage by thrombin, Factor Xa, Factor IXa or Factor XIIa. Factor VIIa converts Factor X to Factor Xa, which in turn converts prothrombin to thrombin.