MAb to Thrombin Receptor Antibody
Immunoglobulin isotype
IgG1
Clone
B825M
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Also known as
Thrombin Receptor
Subcategory
Mnoclonal antibodies
Purification method
Protein A chromatography
Concentration
0.2mg/ml (prior to lyophilization)
Tested applications:
Flow Cytometry, Immunoprecipitation, Western Blot
Other gene names
F2R; thrombin receptor; TR; HTR; CF2R; PAR1; PAR-1; N/A
Gene name synonims
F2R; thrombin receptor; TR; HTR; CF2R; PAR1; PAR-1; N/A
Gene name
F2R; thrombin receptor; TR; HTR; CF2R; PAR1; PAR-1; N/A
Form/Appearance
Purified, Lyophilized Reconstitute with 1ml distilled water.
Host organism
Mouse (Mus musculus). Hybridization of Sp2 myeloma cells with spleen cells from BALB/c mice. Source: Ascites
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Species reactivity
N/A; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
thrombin receptor; Thrombin receptor protein; proteinase-activated receptor 1; thrombin receptor; OTTHUMP00000161974; protease-activated receptor 1; coagulation factor II receptor; coagulation factor II (thrombin) receptor; N/A
Storage and shipping
Store lyophilized product at 2 to 8 degree C. After reconstitution, aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Avoid multiple freeze/thaw cycles. The addition of 0.1% (w/v) sodium azide is recommended for storage (up to one month) at 2 to 8 degree C.
Specificity and cross-reactivity
Thrombin Receptor Recognizes an epitope on the receptor, distant from the N-terminal thrombin cleavage site (WEDEE). It reacts with both intact and cleaved receptors.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.