Thrombin receptor Antibody, FITC Conjugated

Thrombin receptor Antibody, FITC Conjugated

Size

0.1ml

Catalog no.

bs-0828R-FITC

Price

333 EUR

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Gene ID number

2149

Conjugation

FITC

Modification site

None

Swiss Prot

P25116

Tested applications

IF(IHC-P)

French translation

anticorps

Modification

Unmodified

Clonality

Polyclonal

Immunogen_range

290-315/425

Excitation Emission

494nm/518nm

Concentration

1ug per 1ul

Target Antigen

Thrombin receptor

Crossreactivity

Human, Mouse, Rat

Additional conjugation

Anti-FITC Antibody

Subcellular location

Cytoplasm, Helical

Recommended dilutions

IF(IHC-P)(1:50-200)

Clone

Polyclonal antibody

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Purification method

This antibody was purified via Protein A.

Long name

Thrombin receptor Polyclonal Antibody, FITC Conjugated

Source

KLH conjugated synthetic peptide derived from human PAR1

Specificity

This is a highly specific antibody against Thrombin receptor.

Crossreactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Synonyms

TR; HTR; CF2R; PAR1; PAR-1; Proteinase-activated receptor 1; Coagulation factor II receptor; Thrombin receptor; F2R

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

Antigen background

High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.

Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.