Thrombin receptor Antibody, Biotin Conjugated
Excitation Emission
N/A
Gene ID number
2149
Modification site
None
Conjugation
Biotin
Swiss Prot
P25116
Tested applications
WB, IHC-P
French translation
anticorps
Modification
Unmodified
Clonality
Polyclonal
Immunogen_range
290-315/425
Concentration
1ug per 1ul
Additional conjugation
Biotinylated
Target Antigen
Thrombin receptor
Crossreactivity
Human, Mouse, Rat
Subcellular location
Cytoplasm, Helical
Clone
Polyclonal antibody
Category
Conjugated Primary Antibodies
Host Organism
Rabbit (Oryctolagus cuniculus)
Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500)
Purification method
This antibody was purified via Protein A.
Source
KLH conjugated synthetic peptide derived from human PAR1
Long name
Thrombin receptor Polyclonal Antibody, Biotin Conjugated
Specificity
This is a highly specific antibody against Thrombin receptor.
Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Synonyms
TR; HTR; CF2R; PAR1; PAR-1; Proteinase-activated receptor 1; Coagulation factor II receptor; Thrombin receptor; F2R
Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
Antigen background
High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.