Thrombin receptor Antibody, Biotin Conjugated

Thrombin receptor Antibody, Biotin Conjugated

Size

0.1ml

Catalog no.

bs-0828R-Biotin

Price

333 EUR

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Excitation Emission

N/A

Gene ID number

2149

Modification site

None

Conjugation

Biotin

Swiss Prot

P25116

Tested applications

WB, IHC-P

French translation

anticorps

Modification

Unmodified

Clonality

Polyclonal

Immunogen_range

290-315/425

Concentration

1ug per 1ul

Additional conjugation

Biotinylated

Target Antigen

Thrombin receptor

Crossreactivity

Human, Mouse, Rat

Subcellular location

Cytoplasm, Helical

Clone

Polyclonal antibody

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Recommended dilutions

WB(1:100-1000), IHC-P(1:100-500)

Purification method

This antibody was purified via Protein A.

Source

KLH conjugated synthetic peptide derived from human PAR1

Long name

Thrombin receptor Polyclonal Antibody, Biotin Conjugated

Specificity

This is a highly specific antibody against Thrombin receptor.

Crossreactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Synonyms

TR; HTR; CF2R; PAR1; PAR-1; Proteinase-activated receptor 1; Coagulation factor II receptor; Thrombin receptor; F2R

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

Antigen background

High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.

Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.

Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.