Thrombin receptor Antibody, Cy5 Conjugated
Conjugation
Cy5
Gene ID number
2149
Modification site
None
Additional conjugation
Cy5.5
Swiss Prot
P25116
Tested applications
IF(IHC-P)
French translation
anticorps
Modification
Unmodified
Clonality
Polyclonal
Immunogen_range
290-315/425
Concentration
1ug per 1ul
Excitation Emission
625,650nm/670nm
Target Antigen
Thrombin receptor
Crossreactivity
Human, Mouse, Rat
Subcellular location
Cytoplasm, Helical
Recommended dilutions
IF(IHC-P)(1:50-200)
Clone
Polyclonal antibody
Category
Conjugated Primary Antibodies
Host Organism
Rabbit (Oryctolagus cuniculus)
Purification method
This antibody was purified via Protein A.
Long name
Thrombin receptor Polyclonal Antibody, Cy5 Conjugated
Source
KLH conjugated synthetic peptide derived from human PAR1
Specificity
This is a highly specific antibody against Thrombin receptor.
Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Synonyms
TR; HTR; CF2R; PAR1; PAR-1; Proteinase-activated receptor 1; Coagulation factor II receptor; Thrombin receptor; F2R
Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
Antigen background
High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.