Thrombin heavy chain Antibody, Cy7 Conjugated
Additional conjugation
Cy7
Conjugation
Cy7
Modification site
None
Gene ID number
2147
French translation
anticorps
Tested applications
IF(IHC-P)
Modification
Unmodified
Clonality
Polyclonal
Concentration
1ug per 1ul
Excitation Emission
743nm/767nm
Crossreactivity
Human, Mouse, Rat
Recommended dilutions
IF(IHC-P)(1:50-200)
Clone
Polyclonal antibody
Target Antigen
Thrombin heavy chain
Category
Conjugated Primary Antibodies
Host Organism
Rabbit (Oryctolagus cuniculus)
Purification method
This antibody was purified via Protein A.
Long name
Thrombin heavy chain Polyclonal Antibody, Cy7 Conjugated
Specificity
This is a highly specific antibody against Thrombin heavy chain.
Source
KLH conjugated synthetic peptide derived from human Thrombin heavy chain
Conjugated
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
Synonyms
coagulation factor II; prothrombin; F2; Cf-2; Cf2; FII; F 2; coagulation factor II thrombin; Coagulation factor II; Coagulation factor II precursor; F2; Factor II; Factor-II; Prothrombin; prothrombin B-chain; PT; serine protease; THRB; THRB_HUMAN; Thrombin; Thrombin heavy chain.
Antigen background
Thrombin is the final protease in the blood coagulation cascade and serves both pro- and anticoagulant functions through the cleavage of several targets. The ability of thrombin to specifically recognize a wide range of substrates derives from interactions which occur outside of the active site of thrombin. Thrombin possesses two anion binding exosites which mediate many of its interactions with cofactors and substrates, and although many structures of thrombin have been solved, few such interactions have been described in molecular detail. Glycosaminoglycan binding to exosite II of thrombin plays a major role in switching off the procoagulant functions of thrombin by mediating its irreversible inhibition by circulating serpins and by its binding to the endothelial cell surface receptor thrombomodulin.