F2
2147
1-622
Human
P00734
4503635
1 mg/mL
Chicken
anticorps
Polyclonal
in solution
NP_000497.1
Homo sapiens
Western Blot
unlabelled serum
70 kDa (calculated)
Immunoaffinity Purified
coagulation factor II (thrombin)
Prothrombin, Coagulation factor II, Prothrombin
Phosphate-Buffered Saline. No preservatives added.
Prothrombin antibody can be used for the detection of Prothrombin by Western Blot.
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
F2 antibody can be stored at 4 grades C for short term (weeks). Long term storage should be at -20 grades C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
FUNCTION: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C.DISEASE: Defects in F2 are the cause of various forms of dysprothrombinemia [MIM:176930].CATALYTIC ACTIVITY: Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B.