Thrombin receptor Antibody
Gene ID number
2149
Modification(s)
None
Swiss Prot
P25116
French translation
anticorps
Immunogen range
290-315/425
Concentration
1ug per 1ul
Conjugation
Unconjugated
Target Antigen
Thrombin receptor
Cross reactivity
Human, Mouse, Rat
Category
Primary Antibodies
Subcellular location
Cytoplasm, Helical
Modification site(s)
Unmodified antibody
Clonality
Polyclonal antibody
Clone number
Polyclonal antibody
Tested Applications
WB, IHC-P, IF(IHC-P)
Also known as
Thrombin receptor PAb
Purification method
This antibody was purified via Protein A.
Long name
Thrombin receptor Primary Polyclonal Antibody
Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Specificity
This is a highly specific antibody against Thrombin receptor.
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Synonym names
TR; HTR; CF2R; PAR1; PAR-1; Proteinase-activated receptor 1; Coagulation factor II receptor; Thrombin receptor; F2R
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PAR1
Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Background of the target antigen
High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.