Thrombin receptor Antibody

Thrombin receptor Antibody

Size

0.1ml

Catalog no.

bs-0828R

Price

263 EUR

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Gene ID number

2149

Modification(s)

None

Swiss Prot

P25116

French translation

anticorps

Immunogen range

290-315/425

Concentration

1ug per 1ul

Conjugation

Unconjugated

Target Antigen

Thrombin receptor

Cross reactivity

Human, Mouse, Rat

Category

Primary Antibodies

Subcellular location

Cytoplasm, Helical

Modification site(s)

Unmodified antibody

Clonality

Polyclonal antibody

Clone number

Polyclonal antibody

Tested Applications

WB, IHC-P, IF(IHC-P)

Also known as

Thrombin receptor PAb

Purification method

This antibody was purified via Protein A.

Long name

Thrombin receptor Primary Polyclonal Antibody

Recommended dilutions

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Specificity

This is a highly specific antibody against Thrombin receptor.

Cross reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Synonym names

TR; HTR; CF2R; PAR1; PAR-1; Proteinase-activated receptor 1; Coagulation factor II receptor; Thrombin receptor; F2R

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PAR1

Storage conditions

Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.

Properties

If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Background of the target antigen

High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.

Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.